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1999 Selected Abstracts
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Durability of Results in 134 Patients Treated with Transurethral Microwave Thermotherapy (TARGIS(r)) for Benign Prostatic Hyperplasia (BPH) |
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| A Bitton; GN Thalmann; SF Graber; S Wille; FC Burkhard; O GrŸnig UE StŸder; Department of Urology, Berne, Switzerland (Presented by Dr. Thalmann) | ||||
| Introduction: Since 04/1995 we offer thermotherapy as an alternative treatment for patients with symptomatic BPH who are medically unfit. We evaluated the first 100 patients with 12 months follow-up. | ||||
| Methods: Between 04/1995 and 10/1997, 134 men with a median age of 73 years (52-91) with cystoscopically documented BPH underwent transurethral microwave thermotherapy with the Targis(r) system. Inclusion criteria required an AUA Symptom Score 9 and a Q Max 12 ml/sec. Pre and post-treatment evaluation was made with the International Prostate Symptom Score (IPSS-S) and quality of life score (IPSS-L), uroflowmetry, transrectal ultrasonography (TRUS) and cystoscopy. A pressure-flow study was performed before treatment and at 6 and 24 months of follow-up. | ||||
| Results: Of the first 134 patients, 100 were evaluable at 12 months and 30 at 24 months posttreatment. Twenty four patients (18%) were anticoagulated, 67 (50%) had an ASA score 3. The median amount of energy delivered was 141 KJ (73-250). So far, 3 patients (2.2%) have reported an anejaculation. Two patients (1.5%) required a second thermotherapy and 11 patients (8.2%) a TURP. All changes between the pre and posttreatment values were statistically significant (p<0.00001) | ||||
| Median values | Preop
(n=100) | 6 months
(n=100) | 12 months
(n=100) | 24 months
(n=30) |
| IPSS-S score | 23 | 4 | 4 | 3 |
| IPSS-L score | 4 | 1 | 1 | 1 |
| Q (ml/sec) | 7 | 15 | 14 | 12 |
| Residual (ml) | 199 | 35 | 39 | 25 |
| Prostate size (cc) | 58 | 32 | 34 | 36 |
| Pdet at Q max (cmH2O) | 99 | 61 | – | 52 |
| Conclusions: Transurethral microwave thermotherapy fulfills the criteria for a minimally invasive treatment of BPH. This method is especially useful in patients who are either medically unfit or unwilling to undergo general or spinal anesthesia, or for younger patients who are concerned about anejaculation. Long-term results seem to be durable. | ||||
| Source: 1999 AUA Meeting | ||||
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