The Prostatitis Foundation
 

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Melatonin and Prostatitis

I'm a 35 year old male from Israel. I had a few episodes of Prostatitis a few years ago, and had been suffering from symptoms ever since. Recently I had some unrelated sleeping problems and was subscribed by my doctor a new medicine that is based on Melatonin (but in a time-released manner). My sleep problem did improve, but what was really amazing is that all my Prostatitis symptoms disappeared all together within a few days of taking the pills. I still find it hard to believe, but it's the truth.
 
The name of the medicine I was given is Circadin®. You can read more about it here:
 
http://www.neurim.com/products.asp
 
As far as I know it is not currently sold in the US, but I think it is expected to be on the market some time soon.
 
Hope this helps someone.
  
some background info I've found on the web about the connection between Melatonin and the Prostate:
 
The prostate actually contains melatonin receptors that make melatonin necessary for the prostate to function. You have to do an in-depth search of the scientific literature to find out how important melatonin is to prostate function.
 
There have been many studies in laboratory animals showing that melatonin in varying doses could lower prostate weight and shrink the prostate, thus facilitating the prevention of prostate cancer. These studies have been published in such journals as Endocrinology, Progress in Brain Research, Experientia, Hormone Research, Archiva Farmacologia Toxicology, Hormone Metabolism Research, Journal of Pineal Research, Journal of Urology, European Journal of Pharmacology and many others. This clearly shows the value of melatonin in prostate disease. More recently human studies have been done. At the University of Tuebingen in Germany men with prostate cancer were found to have low melatonin levels (Clin. Chim. Acta 209 (1992) p. 153-67). In a later study at the same university (Int. Cong. Series 1017 (1993) p. 311-6), they found the same phenomenon and suggested using melatonin supplements to treat prostate cancer.
 
At the University of Lodz in Poland researchers came to the same conclusion to use melatonin to treat prostate cancer (Int. J. Thymol. 4 (1996) p. 75-9). Studies in Endocrinology, Journal of Clinical Endocrinology and Metabolism, Frontiers of Hormone Research and others have found definite melatonin receptors in the prostate gland proving how important this hormone is for proper function, regulation and metabolism.
 
At Tel Aviv University in Israel studies showed that melatonin receptors in human prostates can suppress prostate enlargement. They noted that BPH is due to the imbalance of estrogen and testosterone as we age and found that this excess estrogen also interferes with normal melatonin metabolism (J. Clin. Endoc. Metab. 82 (1997) p. 25 35 - 41).  

 

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