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Ongoing Studies in Male Chronic Pelvic Pain

(MCPP; Prostatitis)
at the Department of Urology,
University of Washington
(updated 2/18/00)
Prostatitis, or Male Chronic Pelvic Pain (MCPP) is a common and distressing problem for many men. It is characterized by chronic pain in the genital and surrounding area and is frequently associated with urinary problems such as frequent and urgent urination, pain with urination, and others. Dr. Richard E. Berger of the University of Washington's Urology Department has a special interest in Prostatitis/MCPP, and has a clinical and research program that meets the needs of men with this condition. He and his staff are currently running two studies to evaluate and treat MCPP.
  1. Evaluation Study: This study involves a thorough evaluation for potential cofactors of MCPP. The study includes:

    • Systematic history-taking and documentation of symptoms;

    • Evaluation for lower genitourinary tract infection using the latest available clinical and research techniques;

    • Standardized physical examination;

    • Standardized evaluation of pelvic musculoskeletal function by a physical therapist;

    • Neurophysiologic testing of the lower genital tract;

    • Biochemical analysis of prostatitc fluid and semen for reactive oxygen species (experimental), fertility parameters, and other inflammatory markers;

  2. Treatment Study: "N=1"

    N=1 means you are the subject that receives BOTH active treatment AND placebo. Subjects in this study act as their own controls to test the hypothesis that certain medications can alleviate the symptoms of MCPP. They receive either medication or placebo for one week and then are switched to another medication or placebo. At the end of the study subjects are presented with a statistical analysis of "their" data to help them decide if treatment is effective.
The medications currently being evaluated are: montelukast, celecoxib, oxybutinin, and tamsulosin. Subjects will also be given the opportunity to evaluate other medications using this same methodology.
Those interested in participating in any of these studies should contact
Margaret Frest , Research Coordinator,
Dept of Urology, University of Washington
Seattle, WA, 98195-6510
Voicemail: (206)-598-6357
Email:prostate @ u.washington.edu

This information is forwarded to you by the Prostatitis Foundation. We do not provide medical advice. We distribute literature and information relevant to prostatitis. While we encourage all research we do not endorse any doctor, medicine or treatment protocol. Consult with your own physician.
© 2002 The Prostatitis Foundation
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