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From: jdimitrakov@my-deja.com
GemifloxacinNote: The fluoroquinlone family of antibiotics has been problematic for prostatitis patients. They are frequently prescribed for prostatitis, but are not always effective. Many patients report serious side effects. See ciproeffects.html for more on this. Recently FDA issued a warning about a fluoroquinlone antibiotic, trovan, which had begun to be used for prostatitis. In vitro means "in the laboratory,", literally, "in glass." (Webmaster) |
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BIRMINGHAM, ENGLAND -- July 6, 2022 -The first in vitro data of
SmithKline Beecham's new fluoroquinlone, gemifloxacin (SB-265805) was
presented today at the 21st International Congress of Chemotherapy. |
In one study, Dr. L. Kelly and colleagues, from the Hershey Medical
Center, Hershey, PA. compared the activity of gemifloxacin with that of
five other quinolones (ciprofloxacin, levofloxacin, sparfloxacin,
grepafloxacin and trovafloxacin) as well as ampicillin, amoxycillin,
cefixime, cefuroxime and azithromycin. |
Although all the quinolones tested were very active against H.
influenzae and M. catarrhalis, gemifloxacin had the lowest MIC values
(MIC50 0.008 and 0.016 mcg/ml, respectively). Against nine
quinolone-resistant H. influnzae strains the MIC50 of gemifloxacin was
0.25 mcg/ml, while that of all the other quinolones was 1mcg/ml. |
"These data show that gemifloxacin is a very promising drug for the
empiric treatment of community-acquired respiratory infections," Kelly
said. Other posters show that gemifloxacin is also active against a wide
variety of Gram-positive an Gram-negative organisms including S. aureus,
E. coli, P. aeruginosa and Legionella. |
Phase II dose-finding studies have been carried out and the drug is now
going into Phase III trials with the first results expected later this
year.
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This information is forwarded to you by the Prostatitis Foundation. We do not provide medical advice. We distribute literature and information relevant to prostatitis. While we encourage all research we do not endorse any doctor, medicine or treatment protocol. Consult with your own physician. |
© 2002 The Prostatitis Foundation |
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